Federico Forneris - Research Investigator
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    e-mail: federico.forneris@unipv.it Phone:+39 0382 985228 |
PERSONAL DETAILS:
- Born Aug 07th, 1978 in Piedmont, Italy
- Languages known: Italian, English, French
- 2023-now: Full Professor (Tenured), University of Pavia, Italy
- 2022-now: President of the INF-ACT Foundation, Pavia, Italy
- 2021-now: Vice-Rector for Research, University of Pavia, Italy
- 2017-2023: Associate Professor (Tenured), University of Pavia, Italy
- 2014-2017: Assistant Professor (Tenure-Track), University of Pavia, Italy
- 2009-2013: Postdoctoral research assistant, University of Utrecht, The Netherlands
- 2007-2009: Postdoctoral research assistant, University of Pavia, Italy
EDUCATION AND TRAINING:
- 2009-2013: Post-doc research in Protein Structural Biology, Crystal and Structural Chemistry, Bijvoet Centre for Biomolecular Research, Utrecht University, The Netherlands
- 2003-2008: PhD research in Basic and Applied Biomolecular Sciences, Institute for Superior Studies (IUSS) and University of Pavia, Italy
Title of Thesis: Investigating the Structural and Biochemical Properties of human Lysine-Specific Demethylase LSD1. - 1997-2002: Master degree in physical chemistry, cum laude with special mention and recommendation for publication, University of Turin, Italy
Title of Thesis: Crystallographic studies of Artificial Metalloproteins with four-helical bundle motifs. - 1992-1997: High school diploma in Accountancy, Istituto Tecnico Commerciale E. Tesauro, Fossano, Italy
RESEARCH SUMMARY:
The common theme of the active research projects of my lab is the elucidation of the intricate mechanisms of extracellular protein-protein interaction and signaling. The various processes that fall under the description of "molecular recognition" (ranging from transient inter-molecular interactions, conformational changes, proteolysis-mediated activation and inhibition, to many others) represent for me one of the most fascinating aspects of nature elegance and complexity. In my research lab, we merge structural biology with biochemistry and biophysics to characterize large macromolecular complexes and elucidate their structure-function relationship to put the molecular insights in the proper biological context. I am co-author of several publications in international peer-reviewed scientific journals of high profile (14 papers as first author) including Science, PNAS, Nature Communications, Science Advances, Science Signaling, Cell Reports, Current Biology J. Neurosci, EMBO J and JACS and 3 book chapters (Complete publications list in Pubmed).
For more information about current research and targets, please visit the Research section of the lab website.