The common theme of the research projects in our groups is the investigation of medically relevant proteins and enzymes with interesting chemical properties, such as complex multifunctional systems and proteins performing unusual catalytic functions. The core of the research activity is represented by the study of three-dimensional structures of macromolecules, using crystallography and cryo- electron microscopy. These methods are integrated by other approaches such as biochemistry, biophysics, cell biology and computational chemistry. Current research includes understanding the reactivity of flavoenzymes with oxygen (Mattevi), extracellular systems involved in signal transduction and in ECM assembly (Forneris), enzymes of the neurotransmitter metabolism (Binda), membrane proteins (Magnani), and protein complexes involved in chromatin remodeling (Mattevi).
10/11/2025 - New people, new projects
After the kick off meeting of Comenze, a European Doctoral Network on enzyme biotechnology, Marta Sundstrom has joined our laboratory as new PhD fellow. You are also welcome to consider the the PhD opportunities that are offered by Haloverse, a European Doctoral Network that will take off in January 2026.
Department of Biology and Biotechnology "L. Spallanzani"
University of Pavia
Via Ferrata, 9
I-27100 PAVIA (Italy)< br>
