33a
Riunione Nazionale(33rd “A. Castellani” Meeting of PhD students in biochemical sciences)
BRALLO DI PREGOLA (Pavia)
6-9 June 2022
~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~
SCIENTIFIC AND ORGANIZING COMMITTEE
Cesare Balduini
Vittorio Bellotti
Roberta Besio
Antonella Forlino
Sofia Giorgetti
Francesco Malatesta
Giampaolo Minetti
Marina Porcelli
Antonio Rossi
Maria Enrica Tira
Francesca Tonelli
Mauro Torti
SCIENTIFIC AND ORGANIZING SECRETARIAT
Università degli Studi di Pavia
Dipartimento di Biologia e Biotecnologie “Lazzaro Spallanzani”
Laboratori di Biochimica
Via A. Bassi, 21 - 27100 PAVIA
Tel. 0382/987236 - Fax 0382/987240
E-mail: riundott@unipv.it - Homepage: http://www.unipv.it/bralweb
~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~
PROGRAM
~-~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~
Long non coding RNAs/miRNA loop in the control of tumour development: new diagnostic and therapeutic tools
Myelin basic protein recovery during PKU mice development and the potential role of microRNAs on its regulation
10:10-10:25
Federica Melisi (Napoli)
Regulatory role of miR-449a as a potential biomarker in head and neck carcinoma
10:25-10:45
Miriam Lucariello (Napoli)
Pharmacological targeting of CtBP1/BARSs protein in cancer and in viral infection
COFFEE BREAK
11:15-11:30
Martina Bevilacqua (Padova)
Extending the repertoire of tandem repeat structures
11:30-11:50
Pamela De Falco (Roma)
Role of NAT8L in the metabolic rewiring of Hepatocellular carcinoma
11:50-12:10
Carlo Caputo (Napoli)
A pilot study of miRNA expression profile in surgically resected pancreatic ductal adenocarcinoma: initial report from a bi-institutional cohort
12:10-12:30
Valentina Daponte (Pavia)
Bone cell differentiation during caudal fin regeneration is differentially affected in two zebrafish models of dominant and recessive Osteogenesis imperfecta
13:00 LUNCH
~-~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~
Nutrition, health and environmental sustainability
ERp57 chaperon protein protects neuronal cells from Aβ-induced toxicity
15:35-15:55
Valentina Mondani (Pavia)
Filling the gap for transthyretin amyloidosis: biochemical and structural studies of in vitro and in vivo assembled amyloid fibrils
15:55-16:10
Carolina Paula Miguel (Pavia)
Bone marrow modeling for platelet production
COFFEE BREAK
16:40-16:55
Elena Palmieri (Trieste)
Investigation of alternative technologies for the development of polysaccharide-based vaccines
16:55-17:15
Emma Veronica Carsana (Milano)
SARS-CoV-2 affects dopamine homeostasis in dopaminergic neurons
17:15-17:30
Roberta Piacentini (Roma)
Lactoferrin inhibition of the complex formation between ACE2 receptor and SARS CoV-2 recognition binding domain
19:30 DINNER
~-~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~
WEDNESDAY, JUNE 8th, 2022
Heme oxygenase and its metabolites: new biological implications
Biocatalytic applications of Lathyrus cicera amine oxidase
10:10-10:25
Martina Roberta Nastasi (Roma)
Cytochrome bd-II oxidase from Escherichia coli shows an additional hydrogen peroxide scavenging activity
10:25-10:40
Maria Laura Matrella (Bari)
Biochemical and molecular characterization of differentiated SH-SY5Y cells as an “in vitro” model in neuroscience researchù
COFFEE BREAK
11:10-11:30
Lorenzo Ceccarelli (Siena)
Human microglia derived Extracellular Vesicles: different donor cells for different content and biological function
11:30-11:45
Silvia Breviario (Milano)
Evaluation of the role of acid sphingomyelinase inhibition in GBA-dependent Parkinson’s disease
11:45-12:00
Rosamaria Militello (Firenze)
Sex-related adaptations to chronic in-season training
12:00-12:15
Chiara Pacelli (Roma)
In silico design and evaluation of exon skipping-inducing antisense oligonucleotides for therapeutic intervention in rare cancers
12:15-12:35
Ignazio Restivo (Palermo)
Cigarette smoke extract-induced eryptosis is modulated by p38 MAPK-ceramide axis and inhibited by indicaxanthin
13:00 LUNCH
~-~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~
14:30-14:45
Filippo Molinari (Varese)
Whole cell biocatalyst for the sustainable production of vanillin and cis,cis-muconic acid
14:45-15:00
Lucia Piazza (Pisa)
Aldose reductase differential inhibitors from natural sources
15:00-15:15
Monica Cozzi (Parma)
Evaluation of disruptors of the protein-protein interaction between human hemoglobin and S. aureus hemophore IsdB by elisa assay and STD-NMR
15:15-15:30
Roberta Seccia (Bari)
Effect of citrate on the Ggc1p transport
15:30-15:50
Massimo Genovese (Firenze)
Looking for new PTP1b and LMW-PTP inhibitors as tools for human chronic diseases treatment: nature is still our best teacher
15:50-16:05
Dorina Dobi (Milano)
CFTR modulators and ganglioside GM1: possible therapeutic approach in cystic fibrosis
COFFEE BREAK
16:40-17:30 Prof. Andrea Segré, Università di Bologna:
Andrea Segré will present his new unreleased book
19:30 DINNER
~-~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~
21:00-23:00 Serata caminetto:
Enviromental impact of population nutrition: a challange for the future
~-~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~
THURSDAY, JUNE 9th, 2022
Structure and function of cytochrome c oxidase, a mysterious enzyme
9:50-10:10
Luca Galgano (Pavia)
Role of the proline-rich tyrosine kinase Pyk2 in platelet activation in a murine model of endotoxemia
10:10-10:25
Gabriele Coluccino (Udine)
Structural role of the N-terminal tail of mitochondrial cyclophilin D: an NMR characterization
10:25-10:45
Chiara Gramegna Tota (Pavia)
Impairment of calcium-activated nucleotidase 1 affects proteoglycan synthesis and cell homeostasis
~-~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~-~