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PROGRAM
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TUESDAY, JUNE 3rd, 2025
17.00-20.00
ARRIVAL AND REGISTRATION
20.00
DINNER
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WEDNESDAY, JUNE 4th, 2025
8.50-9.00
OPENING OF THE MEETING
9.00-9.40
Prof. Michela Tonetti (Università di Genova)
Development of a TGDS knockout zebrafish model for studying the
pathogenesis of Catel-Manzke syndrome
9.40-10.00 Maria Teresa Altieri (Università di Ferrara)
Exploring the TNPO3 influence in LGMDD2 zebrafish model
10.00-10.20 Elisa
Zamprogno (Università di Udine)
Unraveling the correlation between dystonia and autophagic flux via
ATP5CM3 mutations
COFFEE
BREAK
10.50-11.10
Giorgia Guccione
(Università di Genova)
Tackling the NAD-related signaling pathways to counteract
doxorubicin-induced cardiotoxicity
11.10-11.30
Michela Rosiello (Università
di Foggia)
Clockwork cells: circadian control of mitochondrial functions
11.30-11.50
Mirko Tamma (Università
di Foggia)
Circadian mitochondrial dysfunction in cellular models of early-onset
Parkinson’s disease with PARK2 mutations
11.50-12.10
Camilla Maggi
(Università di Brescia)
VEGFR2 R1051Q mutation modifies receptor membrane behavior and cellular
metabolism through heterodimerization
13.00
LUNCH
15.00-15.40 Prof. Mauro Maccarrone (Università dell'Aquila)
Phytocannabinoids, Endocannabinoids and The Challenge of Developing
Selective Drugs
15.40-16.00 Camilla Danisi (Università di Napoli Federico II)
The CAM assay: an in vivo model to evaluate the biocompatibility and the
efficacy of novel therapeutic compounds
16.00-16.20 Gianluca
Morganti (Università di Urbino)
Development of a surface-modified LNP with the aim of crossing the BBB
and releasing ATM-variant mRNA into neuronal cells
COFFEE
BREAK
16.50-17.10
Prof.
Mauro Maccarrone (FEBS Chair of the Advanced Courses Committee)
FEBS Contribution to the Advancement of Molecular Life Sciences
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20.00
DINNER
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21.00-23.00
Serata
caminetto
La collaborazione e la ricerca
scientifica internazionale in tempi di guerra
Interverranno:
Prof. Vittorio Bellotti (Università degli Studi di Pavia)
Prof. Salvatore Zappalà (Università degli Studi di Catania)
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THURSDAY, JUNE 5th, 2025
9.00-9.40
Prof. Adriano Aguzzi (Universitätsspital Zürich, CH)
Functional Genomics of the Prion Life Cycle
9.40-10.00
Irene Balloni (Università di Pisa)
Investigation of the role of the 18 kDa translocator protein in
neuroprotection: new modulatory mechanisms in different neuronal models
of Alzheimer’s disease
10.00-10.20 Gloria Basso (Università di
Pisa)
Adenosine in an in vitro model of lung fibrosis: focus on its effects in
myofibroblast-lipofibroblast trans-differentiation
COFFEE
BREAK
10.50-11.10 Tatiana
Zuppelli (Università di Catania)
Lipocalin-2 and iron metabolism dysregulation promote glioblastoma
progression and resistance to radiotherapy
11.10-11.30 Mario
Cocorullo (Università di Pavia)
Targeting Mycobacterium abscessus
salicylate synthase to disrupt iron acquisition mechanisms employing
FDA-approved drugs
11.30-11.50 Chiara
Motta (Università di Pavia)
A Novel Virulence Mechanism in Staphylococcus
aureus: FnBPA Cross-Linking to Fibrinogen by Bacterially Activated
FXIII and TG2
11.50-12.10 Serena
Rustichelli (IUSS, Pavia)
Natural modulators of platelet activation: antithrombotic potential of
curcumin and its analogues
13.00
LUNCH
15.00-15.40
Prof.ssa
Lucia Longhitano (Università di Catania)
Zebrafish (Danio
rerio): a model for exploring metabolic rewiring in human diseases
15.40-16.00
Giorgia
Casucci (Università di Genova)
Effects of TGDS knockdown in ATDC5 cells’ chondrogenic differentiation
16.00-16.20 Alessandra Sala (Università di
Pavia)
Development of therapeutic approaches to treat osteogenesis imperfecta
16.20-16.40 Aghna
Maryam
(Università di Urbino)
Protective role of nutraceuticals against UV-induced damage in human keratinocytes
COFFEE
BREAK
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17.10-18.00
BLITZ PRESENTATIONS (A)
1
Susan Mirmajidi
(Università di Milano)
Placental endocannabinoid and eicosanoid profiling in maternal obesity
and gestational diabetes
2
Sofia Paola Lombardo
(Università di Catania)
Safety and efficacy profiling of sonoporation as a drug delivery method
in solid tumors
3
Anam Aftab (Università
di Catanzaro Magna Grecia)
Targeting glutamine metabolism to enhance sensitivity to ATR inhibition
in triple-negative breast cancer cells
4
Greta Bertoli
(Università di Siena)
Understanding prostate cancer organotropism: the role of citrate in the
interplay between lung and bone resident cells and metastatic prostate
cancer cells
5
Giuseppe Nicolò Conti
(Università di Catania)
Long-reads RNAseq reveals an isoform switching transcriptional landscape
in irradiated microglia
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20.00
DINNER
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FRIDAY, JUNE 6th, 2025
9.00-9.40
Prof.ssa Marzia Perluigi (Università di Roma La
Sapienza)
Defects of redox homeostasis and bioenergetics in the brain: a dangerous
interplay for cognitive decline
9.40-10.00 Laura Orlando (Università di Catania)
Proteomic analysis profile and oxidative stress in glioblastoma cells
exposed to radiotherapy
10.00-10.20 Federico Marchini (Università di
Siena)
Cystine-dependent metabolic vulnerabilities in mesenchymal stem-like
triple-negative breast cancer: role of NRF2 and EGLN1 in oxidative
stress resistance
COFFEE
BREAK
10.50-11.10 Nicola Masè (Università di
Verona)
Molecular Insights into Redox-Mediated Regulation of a Toxoplasma gondii Cyclophilin
11.10-11.30 Clelia Cortese (Università di Siena)
HPLC and MALDI-TOF analysis of promising new antimicrobial peptides for
stability assessment against specific protease activity at infection
sites
11.30-11.50 Angelo Sparti (Università di
Urbino)
Investigating the therapeutic potential of a novel fully human IgG4
anti-CD99 antibody through functional and phenotypic characterization in
acute myeloid leukemia and immune cells
11.50-12.10 Enrico La Spina (Università di
Catania)
Tumour Neutrophyls Mitochondrial
Dysfunction and SYK/STAT5/NLRP3 Activation in Myelofibrosis:
Impact of Ruxolitinib on NETs Formation and Bone Marrow Inflammation
13.00
LUNCH
15.00-15.40
Prof.
Luca Bini (Università di Siena)
Extensive Proteomic Approach: a tool to open new perspectives in the study
of viral infections
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17.00-18.00
BLITZ PRESENTATIONS (B)
1
Martina Codibue
(Università di Brescia)
Gremlin-1 promotes the acquisition of an inflammatory, oxidative and
mesenchymal phenotype in 3T3-L1-derived adipocytes possibly via
BMP-independent molecular pathways
2
Stefano Putaggio
(Università di Messina)
Impact of catechin and epicatechin on AE1 functionality of human red
blood cells
3
Elisa Moreschi
(Università di Brescia)
Development of polypyrrole-based actuator to deepen the effects of
tumoral extracellular matrix remodeling on endothelial cells
4
Ilenia Paoletti
(Università di Foggia)
Exploring the effects of β-hydroxybutyrate on a new in vitro model
of human hippocampal neurogenesis
5
Gabriele Paolozzi
(Università di Roma La Sapienza)
Quantitative proteomics reveals BVRA as a key protein in mitochondrial
metabolism
6
Federica Di Padua
(Università di Ferrara)
Anti-inflammatory effects of S-1-propenyl-L-cysteine, a major costituent
of aged garlic extract: reversion of the proinflammatory mRNA
up-regulation induced in human bronchial epithelial IB3-1 cells by the
COVID-19 BNT162b2-vaccine
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COFFEE
BREAK
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20.00
DINNER
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SATURDAY, JUNE 7th, 2025
9.00-9.40
Prof. Alessando Prinetti (Università di Milano)
Cross talk between different cell populations in myelin repair:
sphingolipids conduct the orchestra
9.40-10.00
Cosimo Damiano
Perrone (Università di Siena)
SNIPR-driven orthogonal genetic circuits for tumor-specific sensing in
lymphocytes
10.00-10.20 Wendy Pérez Franco (Università di
Pavia)
Unrevealing the multi-organ consequence of osteogenesis imperfecta in
aging
10.20-10.40 Asifa Khan
(Università di Pavia)
Insights in the musculoskeletal phenotype of an animal model of
diastrophic dysplasia
10.40 CLOSING REMARKS
11.00 DEPARTURE
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SCIENTIFIC AND ORGANIZING COMMITTEE
Vittorio Bellotti
Antonella
Forlino
Antonio
Rossi
Giampaolo Minetti
Maria Enrica Tira
Mauro Torti
Santina
Bruzzone
Giovanni
Li Volti
Chiara
Schiraldi
