32^a Riunione Nazionale
"A. Castellani"
dei Dottorandi di Ricerca in
Discipline Biochimiche

(32^nd “A. Castellani” Meeting of PhD students in biochemical sciences)

SCIENTIFIC AND ORGANIZING COMMITTEE

Cesare Balduini
Vittorio Bellotti
Roberta Besio
Ilaria Canobbio
Nazzareno Capitanio
Antonella Forlino
Gianfranco Gilardi
Sofia Giorgetti
Gianni Guidetti
Palma Mangione
Giampaolo Minetti
Giampiero Pietrocola
Marina Porcelli
Sara Raimondi
Antonio Rossi
Annalisa Santucci
Maria Enrica Tira
Mauro Torti
Simona Viglio

 SCIENTIFIC AND ORGANIZING SECRETARIAT

Università degli Studi di Pavia

Dipartimento di Biologia e Biotecnologie “Lazzaro Spallanzani”

Laboratori di Biochimica

Via A. Bassi, 21 - 27100 PAVIA

 Tel. 0382/987236 - Fax 0382/987240

E-mail: riundott@unipv.it  - Homepage: http://www.unipv.it/bralweb

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PROGRAM

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                       MONDAY, SEPTEMBER 13^th, 2021

 17.00-20.00   Registration & check-in

 20:00             DINNER

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                       TUESDAY, SEPTEMBER 14^th, 2021

 8.50-9.00       Opening remarks

 Chair:            Vittorio Bellotti

 9.00-9:50       Prof. ILDIKO SZABO (Padova)
Mitochondrial ion channels: linking biophysics to bioergenetics and pathologies

 09.50-10.10   Chiara D'Aprile (Milano)
Effect of a remyelination promoting antibody on the sphingolipid pattern of a microglial cell line

 10.10-10.30   Lorenzo Germelli (Pisa)
The 18-kDa translocator protein (TSPO) promotes microglia neurosteroidogenesis to restore CNS homeostasis

                       COFFEE BREAK

 Chair:           

 11.20-11.40   Ignazio Restivo (Palermo)
Cigarette smoke extract induces eryptosis by death-inducing-signaling-complex (DISC) assembly leading to ceramide formation and p38 MAPK activation

 11.40-12.00   Dorina Dobi (Milano)
CFTR modulators and sphingolipids: new insight in the treatment of cystic fibrosis

 12.00-12.20   Emma Veronica Carsana (Milano)
GCase-related pathologies and neurodegeneration: plasma membrane and metabolic implications

                         LUNCH

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Chair:           

 14.30-15.20   Prof. GENNARO CILIBERTO (Roma/Catanzaro)
Birth, development and glory of genetic vaccines and the seminal contribution of an Italian group

 15.20-15.40   Camilla Isgrò (Bari)
Searching for effective inhibitors of the main protease (Mpro) of SARS-CoV-2: an in silico and in vitro study

 15.40-16.00   Tania Vanzolini (Urbino)
In vitro activity of Dia-T51, the new humanized monoclonal antibody against β-1,3-glucans of pathogenic fungi

                       COFFEE BREAK

 Chair:           

 16.00-16.20   Emanuele Criscuolo (Roma)
In silico and in vitro analysis of major cannabis-derived compounds as tools to modulate fatty acid amide hydrolase

 16.20-16.40   Marina Fava (Teramo)
Endocannabinoid and pro-resolving lipid mediators act sinergically in primary human macrophages

     19:30             DINNER

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 21.00-23.00   Serata caminetto:
Ruolo della comunicazione scientifica in una virtuosa relazione
scienza-società

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                      WEDNESDAY, SEPTEMBER 15^th, 2021

   Chair:           

 9.00-10:00     Prof. GIUSEPPE DE NICOLAO (Pavia)
Artificial intelligence for biomedicine: boundaries, horizons, limits

 10:00-10.25   Claudia Grillo (Torino)
Directed evolution on cytochrome P450 BM3 A2 mutant

 10.25-10.50   Marco Minacori (Roma)
β-hexachlorocyclohexane induces STAT3-mediated chemoresistance in HER2-positive cancer cells

                       COFFEE BREAK

 Chair:           

 11.20-11.45   Vitale Del Vecchio (Napoli)
β2-AR blockade potentiates ERK/MEK inhibitors effect on HNSCC by regulating Nrf2-mediated defense mechanism

 11.45-12.10   Glenda Oliveira (Milano)
Defining the molecular landscape of reparative cardiac cells by MS-imaging and advanced MS-proteomics approaches

 12.10-12.35   Eleonora Quartieri (Parma)
NMR metabolic profiling of whole, parotid and submandibular/sublingual saliva for diagnostics purpose

                         LUNCH

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 Chair:           

 14.30-15.20   Prof. PAOLA CHIARUGI (Firenze)
Tumor metabolic deregulation: lactate and its unconventional role

 15.20-15.40   Vanna Denti (Milano)
MALDI-MSI analysis of lipid alterations in FFPE patient-derived breast cancer xenograft for pre-clinical and clinical application

 15.40-16.00   Assia Duatti (Firenze)
Stromal lactate promotes prostate cancer aggressiveness by enhancing collagen-dependent cancer cell colonization

                       COFFEE BREAK

 Chair:           

 16.00-16.20   Francesca Vitiello (Napoli)
Antitumor activity of AdoMet through the modulation of miRNA888-5p in laryngeal carcinoma cells

 16.20-16.40   Stefano Zoroddu (Sassari)
Antineoplastic properties of new synthetic molecules

 16.40-17.10   Alfredo Smiriglia (Firenze)
Studying the role of estrogens using a human embryonic pluripotent stem cell model of non-alcoholic fatty liver disease

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                      THURSDAY, SEPTEMBER 16^th, 2021

   Chair:           

 9.00-9.50       Prof. ANDREA BELLELLI (Roma)
Thioredoxin reductase: functions, catalytic mechanisms and inhibitors

 9.50-10.10     Anastasia Ricci (Urbino)
DDIT4 gene expression is switched on by a new HDAC4 function in ataxia teleangiectasia

 10.10-10.30   Maria Rosaria Coppola (Genova)
Development of a zebrafish model for Catel-Manzke disease

 10.30             CLOSING REMARKS

                       COFFEE BREAK AND DEPARTURE

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  Download the program

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                                                       Web support  

                                               

Studio Congressi Srl, V.le della Libertà, 17 - 27100 PAVIA

www.studio-congressi.com

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